Sperm impairing microbial factor: potential candidate for male contraception
نویسندگان
چکیده
منابع مشابه
Sperm Proteomics: Road to Male Fertility and Contraception
Spermatozoa are highly specialized cells that can be easily obtained and purified. Mature spermatozoa are transcriptionally and translationally inactive and incapable of protein synthesis. In addition, spermatozoa contain relatively higher amounts of membrane proteins compared to other cells; therefore, they are very suitable for proteomic studies. Recently, the application of proteomic approac...
متن کاملSperm specific proteins-potential candidate molecules for fertility control
The increase in population growth rate warrants the development of additional contraceptive methods that are widely acceptable, free from side effects and less expensive. Immunocontraception, and in particular the targeting of antibodies to gamete-specific antigens implicated in sperm egg binding and fertilization, offers an attractive approach to control fertility. The development of a contrac...
متن کاملMale Contraception
Very few options for men to initiate fertility control are currently available. Due to the potential public health impact of a novel method of contraception for men in the developed and developing world, a number of organizations are conducting or supporting studies which focus on the male contraceptive aspect of reproductive health. These include bilateral and multilateral donors, national gov...
متن کامل[Male contraception].
Clear evidence shows that many men and women would welcome new male methods of contraception, but none have become available. The hormonal approach is based on suppression of gonadotropins and thus of testicular function and spermatogenesis, and has been investigated for several decades. This approach can achieve sufficient suppression of spermatogenesis for effective contraception in most men,...
متن کاملIndenopyride derivative RTI-4587-073(l): a candidate for male contraception in stallions.
The objective of this study was to determine whether an indenopyridine derivative RTI-4587-073(l) was a good candidate for male contraception in horses. We hypothesized that a single administration of RTI-4587-073(l) causes significant suppression of testicular function in stallions without affecting sexual behavior. Three Miniature horse stallions received a single dose of 12.5 mg/kg RTI-4587-...
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ژورنال
عنوان ژورنال: Reproductive Biology and Endocrinology
سال: 2020
ISSN: 1477-7827
DOI: 10.1186/s12958-020-00654-4